Pathobiology & Toxicological Pathology

Aim of the course

At the end of the course Pathobiology & Toxicological Pathology, the participants will have a basic understanding of general and toxicological pathology and will have acquired sufficient knowledge to understand and interpret pathological data in papers and reports.

During the course, the fundamental processes of tissue degeneration, cell pathology, inflammation, circulation disturbances and tumor development will be addressed in a series of lectures and practical sessions. Special attention will be given to the underlying mechanisms of pathology, induced by xenobiotics.

After finishing this course, the participants will have a basic understanding of:

  • The anatomy and histology of commonly used laboratory animals.
  • The principal aspects of tissue degeneration, cellular pathology, inflammatory reactions, circulatory problems and neoplasia.
  • The macroscopic and microscopic aspects of several pathological processes.
  • The general procedures used in clinical/diagnostic and toxicological pathology.

Coordinator: Dr. A.L. Menke

Lecturers
Dr. A.L. Menke (PhD, Pathologist, Toxicologist), Dept. of Metabolic Health Research, TNO Leiden, Coordinator
Prof. Dr. D. Salvatori (DVM, PHD, Pathologist), Dept. of Comparative Anatomy & Physiology, Veterinary Medicin, Utrecht University
Dr. M. Ploeg (DVM, PhD, Pathologist), IDEXX Laboratories Limited, Hoofddorp
E. Pieterman (BSc), Dept. of Metabolic Health Research, TNO Leiden
Dr. T. Radonic (MD, PhD, Pathologist), Dept. of Pathology, Amsterdam UMC
Dr. R. Thomas (DVM, Pathologist), Dept. of Veterinary Medicin, Utrecht University
Dr. M. Wijnands (DVM, PhD, Pathologist), Charles River Laboratories, Den Bosch
Prof. Dr. A. Gröne (DVM, PhD, Pathologist), Dept. Of Pathobiology, Veterinary Medicin, Utrecht University.
Dr. S. Maes (DVM, PhD, Pathologist), IDEXX Laboratories Limited, Hoofddorp

Examination
The students will participate in a workshop addressing the toxicity of a present-day xenobiotic and will be asked to give a presentation on the subject. In addition, the participants will have to pass a written examination (self study) that has to be handed in 14 days after the final course day.

Please note that the course can be cancelled up to one month before its starting date, when the number of applications is below the minimum required. For general inquiries please contact the PET Office.

Pharmaceutical Toxicology
Organ Toxicology