Course: Organ Toxicology

This postgraduate course will deal with the physiology and pathophysiology of organ systems. The starting point will be the normal physiology of the organ and its role in the organism’s homeostasis. Different forms of organ dysfunction and its consequences for the organism will be treated, as well as ways of detecting, diagnosing and interpreting organ dysfunction.

Students will receive subjects for self-study in subgroups culminating in presentations on Friday.

Brief description

This postgraduate course will deal with the physiology and pathophysiology of organ systems. This year’s course will focus on the liver, the kidney, the respiratory system , blood (and the hematopoietic system), the bone, the endocrine system and the nervous system. The starting point will be the normal physiology of the organ and its role in the organism’s homeostasis. Different forms of organ dysfunction and its consequences for the organism will be treated, as well as ways of detecting, diagnosing and interpreting organ dysfunction.

Students will receive subjects for self-study in subgroups culminating in presentations on Friday afternoon.

General aims

Insight in pathophysiology of organ systems, with emphasis on the liver, the kidneys, the respiratory system, the nervous system, bone, the endocrine system and the blood system.

Application of this insight in understanding the pathology of intoxications.

Module outcomes (competences, skills)

On successful completion of the module, participants should:

- have obtained knowledge and insight in pathophysiological processes underlying intoxications

- be able to interpret the pathology of intoxications at the level of organ systems

- be able to apply the obtained insights in case studies and be able communicate this to fellow-participants

Lecturers:

Dr. Ir. J.H.E. Arts, AKZO Nobel, Arnhem

Prof dr B.J. Blaauboer, IRAS, Utrecht University

Prof dr G.M. Groothuis, University of Groningen

Dr D.J. van den Dobbelsteen, Schering-Plough, Oss

Dr M. van Duursen, IRAS, Utrecht University

Dr G.J.M.J. Horbach, Schering-Plough, Oss

Dr R Masereeuw, Radboud University Nijmegen

Mr J.E.M. Polman, Schering-Plough, Oss

Dr R.H.S. Westerink, IRAS, Utrecht University

Duration: 1 week

ECTS credits: 1.5

Period: 17-21 January 2011

Fee: € 1,000.= (PhD students may apply for the reduced rate of € 250.=)

Location: Radboud University Nijmegen