Course:
Pathobiology/Toxicological Pathology
Aim of the course:
The Pathobiology/Toxicological Pathology course concentrates
on the fundamental aspects of disease by integrating biochemical, cell biological
and immunological knowledge of disease mechanisms on the levels of cells and
tissues. On this basis the toxicological pathology discipline and its role in
the risk assessment process of xenobiotics will be introduced.
Contents
of the course:
The fundamental processes of disease relate traditionally to
the subjects degeneration and cell pathology, inflammation, circulation
disturbances and tumour development.These subjects will be treated in a series
of lectures and will be illustrated in practical excercises in which
microscopical slides of affected tissues and organs will be studied and
discussed.
Special attention will be given to mechanisms underlying
pathological processes in which toxic compounds have played a role as
pathogenic factors.
Qualifications:
After finishing this course, participants should have a
better understanding of:
·
The
principal aspects of the cellular pathology, inflammatory reactions,
hypersensitivity, circulatory problems en neoplasia.
·
The
general procedures used in clinical/diagnostic and toxicological pathology (
and the application of these techniques/approaches)
·
The
ethical aspects of working with materials/tissues obtained either form animal
or human patients.
·
The
macroscopical as well as of the microscopical histomorfological aspects of
several pathological processes.
Examination:
At the end of the course the participants will be asked to
give an oral presentation with discussion of a subject relevant to the contents
of the course. The topic chosen is the risk assessment of formaldehyde and/or
propylene oxide.
Co-ordinator:
Dr.H.F.J.Dullens
UMC-Utrecht
Departmnent of Pathology
H04.312
Heidelberglaan 100
3584 CX Utrecht
The Netherlands
Tel: (#) 31 (0)88 7556569; e-mail:
h.f.j.dullens@umcutrecht.nl
Lecturers:
Dr.H.F.J.Dullens ( UMC-Utrecht)
Prof. Dr. A. Gröne ( Vet. Fac. UU)
Dr. J. Koninkx ( Vet. Fac. UU)
Dr. C.F. Kuper ( TNO-Voeding)
Dr. E. de Rijk ( Shering-Plough)
Dr.R.A.de
Weger ( UMC-Utrecht)
Dr.R.A.Woutersen ( TNO Voeding)
Duration: 1 week
ECTS credits: 1.5
Period: 4
- 8 October 2010
Fee: €
1,000.- (PhD students may apply for the reduced rate of € 250.=)
Location: